A shaped bottle embryo is a type of embryo that forms during gastrulation. The embryo contains a cluster of cells known as bottle cells that surround the central round cell. The embryo develops along an anterior-posterior axis. Its posterior end points towards the viewer. It is a recognizable feature of the Xenopus embryo.
The embryos were kept in rotating glass bottles which provided oxygen and atmospheric pressure. The biggest challenge was keeping the pressure consistent so that the embryos were properly oxygenated. This is an incredibly delicate process and is not suitable for every embryo. However, the researchers say that this type of research may have surprising applications. For example, the researchers believe that they can grow primitive organs from first-trimester human embryos. This technology has the potential to improve transplant medicine.
Bottles are usually produced through blow molding or injection molding processes. This allows researchers to create embryos before bottle blanks are fully hardened. A general bottle embryo has four parts: an opening, a neck, and a body. The bottom portion is made of plastic. This embryo is then thinned under an internal air pressure and molded into a bottle mold.
A shaped bottle embryo can be a useful research tool. It allows researchers to study embryo development by watching them as they develop. The process can be combined with work on blastoids, which act as imitation embryos.